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Table 3 The numbers of CSF samples among different human prion diseases according to various CH50 value ranges

From: Low activity of complement in the cerebrospinal fluid of the patients with various prion diseases

Groups

CH50 (U/ml) Median (min, max)

P-valuea

CH50 (U/ml) % (case No./group No.)

<100

100–200

200–300

>300

non-CJD

154.066 (12.407–480.312)

-

28.3 % (41/145)

29.7 % (43/145)

24.1 % (35/145)

17.9 % (26/145)

sCJD

108.55 (4.56–474.40)

<0.0001

49.3 % (67/136)

38.2 % (52/136)

7.4 % (10/136)

5.1 % (7/136)

T188K

88.432 (22.39–109.237)

0.0002

92 % (23/25)

8 % (2/25)

0

0

E200K

76.577 (52.03–94.03)

<0.0001

100 % (14/14)

0

0

0

FFI

92.905 (21.43–109.70)

0.0012

77.3 % (17/22)

22.7 % (5/22)

0

0

  1. a Mann–Whitney U test