From: Low activity of complement in the cerebrospinal fluid of the patients with various prion diseases
Groups | CH50 (U/ml) Median (min, max) | P-valuea | CH50 (U/ml) % (case No./group No.) | |||
---|---|---|---|---|---|---|
<100 | 100–200 | 200–300 | >300 | |||
non-CJD | 154.066 (12.407–480.312) | - | 28.3 % (41/145) | 29.7 % (43/145) | 24.1 % (35/145) | 17.9 % (26/145) |
sCJD | 108.55 (4.56–474.40) | <0.0001 | 49.3 % (67/136) | 38.2 % (52/136) | 7.4 % (10/136) | 5.1 % (7/136) |
T188K | 88.432 (22.39–109.237) | 0.0002 | 92 % (23/25) | 8 % (2/25) | 0 | 0 |
E200K | 76.577 (52.03–94.03) | <0.0001 | 100 % (14/14) | 0 | 0 | 0 |
FFI | 92.905 (21.43–109.70) | 0.0012 | 77.3 % (17/22) | 22.7 % (5/22) | 0 | 0 |