Table 4 Multivarivate logistic regression of the levels of CSF CH50 and relational influence factors
From: Low activity of complement in the cerebrospinal fluid of the patients with various prion diseases
Factors | OR 95 % (CI) | P-value | |
|---|---|---|---|
Univariate analysis | Gender | ||
Male | 0.793 (0.456, 1.376) | 0.409 | |
Female | Reference | - | |
Age of onset | |||
<50 | 1.260 (0.343, 4.623) | 0.728 | |
50–70 | 1.503 (0.713, 3.169) | 0.285 | |
>70 | Reference | ||
Codon 129 genotype | |||
Met-Met | 1.114 (0.107, 11.648) | 0.928 | |
Met-Val | Reference | ||
EEG | |||
n.d. | 0.231 (0.127, 1.003) | 0.272 | |
Positive | 0.684 (0.348, 1.346) | ||
Negative | Reference | ||
14–3–3 | 0.003 | ||
Positive | 0.372 (0.195, 0.707) | ||
Negative | Reference | ||
Progressive dementia | 0.814 | ||
Yes | 1.104 (0.485, 2.510) | ||
No | Reference | ||
Myoclonus | 0.703 | ||
Yes | 1.137 (0.588, 2.199) | ||
No | Reference | ||
Visual or cerebellar disturbance | 0.165 | ||
Yes | 0.639 (0.340, 1.202) | ||
No | Reference | ||
Pyramidal or extramidal dysfunction | 0.090 | ||
Yes | 0.602 (0.335, 1.082) | ||
No | Reference | ||
Akinetic mutism | 0.314 | ||
Yes | 0.692 (0.337, 1.419) | ||
No | Reference | ||
multivarivate logistic regression | 14–3–3 | 0.004 | |
Positive | 0.362 (0.182, 0.722) | ||
Negative | Reference |