Skip to main content

Table 1 Characteristics of the study population by HAART status

From: Impact of body fat changes in mediating the effects of antiretroviral therapy on blood pressure in HIV-infected persons in a sub-Saharan African setting

Characteristics

Total (N = 406)

HAART-exposed (N = 306)

HAART-naïve (N = 100)

Gender

   

 Female, n (%)

278 (68.5)

200 (65.4)

78 (78.0)*

 Male, n (%)

128 (31.5)

106 (34.6)

22 (22.0)

Age (years), mean ± SD

37.6 ± 11.2

38.6 ± 10.0

35.6 ± 12.5*

 18–40 years, n (%)

264 (66.0)

189 (62.6)

75 (76.5)

 41–64 years, n (%)

128 (32.0)

108 (35.8)

20 (20.4)

  ≥ 65 years, n (%)

8 (2.0)

5 (1.6)

3 (3.1)

Smoking status, n (%)

   

 Never smokers

354 (89.4)

266 (89.3)

88 (89.8)

 Ever smokers

42 (10.6)

32 (10.7)

10 (10.2)

Weight (kg), mean ± SD

65.8 ± 12.8

65.6 ± 11.6

60.2 ± 12.4**

Height (cm), mean ± SD

163.1 ± 8.4

163.7 ± 8.7

160.3 ± 7.6***

BMI (kg/m2), mean ± SD

24.7 ± 4.6

24.5 ± 4.4

23.4 ± 4.3*

  < 25 kg/m2, n (%)

245 (62.7)

175 (59.7)

70 (71.4)

  ≥ 25 kg/m2, n (%)

146 (37.3)

118 (40.3)

28 (28.6)

WC (cm), mean ± SD

85.9 ± 11.6

86.3 ± 10.3

82.9 ± 12.2**

CD4 count (cells/mm3), mean ± SD

454.1 ± 250.5

439.8 ± 255.5

504.1 ± 226.7***

  < 500 cells/mm3, n (%)

252 (65.3)

200 (66.7)

52 (60.5)

  ≥ 500 cells/mm3, n (%)

134 (34.7)

100 (33.3)

34 (39.5)

HIV duration (months), mean ± SD

45.0 ± 29.4

50.2 ± 29.3

29.0 ± 22.8****

  < 24 months, n (%)

138 (34.9)

88 (29.7)

50 (50.5)

 24–60 months, n (%)

100 (25.3)

65 (22.0)

35 (35.4)

  > 60 months, n (%)

157 (39.8)

143 (48.3)

14 (14.1)

SBP (mmHg), mean ± SD

121.2 ± 18.9

121.8 ± 19.7

112.6 ± 14.3****

DBP (mmHg), mean ± SD

77.4 ± 10.4

78.8 ± 9.9

71.6 ± 8.6****

  1. Comparisons reserved for HAART-exposed versus HAART-naïve patients
  2. Abbreviations: BMI body mass index, DBP diastolic blood pressure, HAART highly active antiretroviral therapy, n number, SBP systolic blood pressure, SD standard deviation, WC waist circumference
  3. *P < 0.05
  4. **P = 0.0001
  5. ***P < 0.01
  6. ****P < 0.00001