Skip to main content

Table 1 Baseline characteristics of ≤ 2-year old malarious children at enrolment according to year and site of study

From: Therapeutic efficacy and effects of artesunate-amodiaquine and artemether-lumefantrine on malaria-associated anaemia in Nigerian children aged two years and under

Study site (year of study)a

No. of children

Gender

Age (year)

Weight (kg)

Duration (days)

Temperature (°C)

Haematocrit (%)

Degree of anaemia

Parasitaemia (μL−1)

M/F

Mean ± sd (Range)

No. <1 year

Mean ± sd (Range)

Mean ± sd (Range)

Mean ± sd (Range)

No. >37.4 °C

No. ≥40 °C

Mean ± sd (Range)

No. < 30 %

Mild

Moderate

Severe

Geometric mean (Range)

No. >100,000 μL−1

Ibadan (2005–2010)

47

26/21

1.7 ± 0.4 (0.7–2)

4

9.7 ± 2.5 (6–17)

2.9 ± 1.5 (1–7)

38.5 ± 1.1 (36.1–40.8)

39

2

28.3 ± 4.5 (20–38)

26

23

3

-

30,924 (1,614–304,500)

7

Damboa (2009–2010)

24

16/8

1.5 ± 0.5 (0.5–2)

7

9.9 ± 3.9 (5–20)

-

37.9 ± 0.6 (37.5–39.3)

24

-

27.9 ± 5.9 (14–36)

12

9

2

1

5,988 (1,000–123,774)

1

Agbani (2009–2010)

57

24/33

1.3 ± 0.5 (0.5–2)

20

9.9 ± 1.7 (5–17)

-

37.6 ± 1.1 (35.6–40.3)

30

1

27.3 ± 4.3 (18–40)

38

33

5

-

10,343 (1,018–155,520)

3

Makarfi (2009–2010)

41

24/17

1.4 ± 0.4 (0.5–2)

15

8.4 ± 1.6 (5–12)

-

37.9 ± 1 (36–39.4)

29

-

29.4 ± 5.1 (16–37)

15

13

2

-

10,208 (1,301–112,421)

2

Ijede (2009–2010)

28

18/10

1.4 ± 0.4 (0.6–2)

6

9.2 ± 1.6 (5–12)

-

38.1 ± 1.4 (36–40.3)

18

4

28.9 ± 4.8 (19–38)

16

14

2

-

10,788 (1,071–78,769)

-

Barkin Ladi (2009–2010)

39

20/19

1.6 ± 0.5 (0.6–2)

8

10.6 ± 2.3 (7–15)

3.1 ± 1 (1–7)

37.9 ± 1 (36.1–40)

30

1

30.7 ± 4.2 (22–40)

13

13

-

-

17,336 (2,132–104,154)

1

Ibadan (2011–2015)

14

11/3

1.4 ± 0.6 (0.5–2)

5

9.2 ± 2.8 (5–14)

3 ± 0.7 (2–4)

38.1 ± 1.3 (36.3–40)

9

1

29 ± 4.1 (22–37)

7

7

-

-

23,326 (2,924–114,504)

-

ALL (2005–2015)

250

139/111

1.5 ± 0.5 (0.5–2)

65

9.6 ± 2.3 (5–20)

3 ± 1.2 (1–7)

38 ± 1.1 (35.6–40.8)

179

9

28.7 ± 4.8 (14–40)

127

112

14

1

13,714 (1000–304,500)

16

P value

-

0.14

0.03

0.03

0.001

0.83

0.01

0.02

0.29

0.03

0.02

0.85

0.99

-

<0.0001

0.11

  1. sd standard deviation
  2. aartesunate-amodiaquine and artemether-lumefantrine were evaluated at all sites