Association between Taenia solium infection and HIV/AIDS in northern Tanzania: a matched cross sectional-study

Table 4 Radiological and serological results of TSOL+ individuals of the matched and initially recruited population

	P 1	P 2	P 3	P 4	P 5	P 6	P 7	P 8	P 9	P 10
Matched study group	yes	yes	yes	yes	yes	yes	yes	yes	no	no
Age	50	46	45	60	46	28	27	51	38	14
Gender	f	m	m	m	m	f	f	m	m	m
First clinical examination
HIV parameters
HIV status	+	+	+	+	-	-	-	-	-	-
HIV stage	I	I	I	III	-	-	-	-	-	-
HAART drugs	ZDV/3TC/EFZ	ZDV/3TC/EFZ	ZDV/3TC/EFZ	ZDV/3TC/EFZ	-	-	-	-	-	-
HAART treatment since (years)	<1	3	3	4	n.a.	n.a.	n.a.	n.a.	n.a.	n.a.
NCC symptoms/signs	-	-	-	headaches	-	severe headaches	-	-	epi	epi, enc^a
CT diagnosis
Calcified cysts	+	-	+	+	o	o	o	o	+	-
Viable cysts	-	-	-	-	o	o	o	o	-	+
Other NCC relevant findings	-	-	-	-	o	o	o	o	-	hydrocephalus
Laboratory diagnosis
CD4⁺ counts	554	433	276	170	n.a.	n.a.	n.a.	n.a.	n.a.	n.a.
CC- Ab	+	+	+	+	+	+	+	+	+	+
CC-Ag	-	-	-	+	-	-	-	-	-	+
Taeniosis-Ab	+	-	-	-	-	-	+	+	+	+
Second clinical examination
NCC symptoms/signs	x	x	-	-	-	severe headaches	-	x	d	epi, enc^a
CT diagnosis								x
Calcified cysts	x	x	+	+	+	-	+	x	d	+
Viable cysts	x	x	-	-	-	-	-	x	d	+
Other NCC relevant findings	x	x	-	-	-	hydrocephalus^b	-	x	d	hydrocephalus
Laboratory findings
CD4⁺ counts	521	400	368	184	n.a.	n.a.	n.a.	n.a.	d	n.a.
CC-Ab	+	+	-	-	+	x	x	x	d	x
CC-Ag	-	-	-	+	-	x	x	x	d	x
Taeniosis-Ab	+	-	-	-	-	x	x	x	d	x
Taeniosis-copro-Ag	-	-	-	-	-	-	-	x	d	x

P patient number, m male, f female, HIV human immunodeficiency virus, HAART highly active antiretroviral therapy, ZDV zidovudine, 3TC lamivudine, EFZ efavirenz, NCC neurocysticercosis, epi epilepsy, enc encephalopathy, CT computed tomography, CD4 ⁺ CD4⁺ T-lymphocyte cell counts, n.a. not applicable, because in the group of HIV– these parameters were not tested and no HAART was taken, CC cysticercosis, Ab antibodies, Ag antigen, + positive, − negative, o was not taken at once due to ethical concerns of performing a CT scan in healthy individuals, but was offered when the positive test serology was confirmed, x patient refused or was not found, d patient died before 2^nd examination with unclear diagnosis (strong headaches and abdominal pain reported before death)
^aPatient was unconscious with signs of brainstem involvement and generalized increased muscle tone leading to flexion contractures of all four limbs, most likely in the context of increased intracranial pressure
^bMass in 4^th ventricle causing obstructive hydrocephalus

ISSN: 2049-9957