Table 4 Features of anaemic patients who recovered from their anaemia and had late fall in haematocrit below 30% (Pattern 3)a
Patient (gender, age) | Year of enrolment | Parasitaemia (Ī¼Lā1) | Enrolment HCT (%) | Antimalarial treatment | PCT (day) | Nadir HCT1 (%) [day] | Nadir HCT2 (%) [day] | HCT on day 42 (%) | AnRT1 (day) | AnRT2 (day) | AUC1 | AUC2 | FIH/1 000 parasites cpb | Total of mg/kg dose of AA | Total of mg/kg dose of AL | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Artesunate | Amodiaquine | Artemether | Lumefantrine | ||||||||||||||
41 (F, 5y) | 2011 | 315 429 | 28 | AA | 1 | 23 [3] | 27[35] | 33 | 14 | 7 | 25.82 | 6.17 | 0.0095 | 11.5 | 31.15 | NA | NA |
12 (M, 1.5y) | 2014 | 98 327 | 25 | AA | 1 | 19 [3] | 26[35] | 28 | 14 | NA | 72.93 | NA | 0.0305 | 9.38 | 25.3 | NA | NA |
33 (M, 2.5y) | 2010 | 70 823 | 28 | AA | 1 | 24 [3] | 28[35] | 28 | 14 | NA | 30.01 | NA | 0.0424 | 12.5 | 33.75 | NA | NA |
219 (F, 3y) | 2008 | 31 640 | 23 | AA | 1 | 23 [0] | 28[21] | 31 | 14 | 7 | 49.83 | 4.67 | 0.0032 | 13.64 | 36.82 | NA | NA |
39 (M, 4.9y) | 2010 | 183 741 | 29 | AA | 1 | 25 [2] | 28[42] | 28 | 7 | Ā | 12.44 | NA | 0.0054 | 8.82 | 23.82 | NA | NA |
15 (M, 1.2y) | 2008 | 72 815 | 27 | AL | 1 | 26 [1] | 28[28] | 33 | 7 | 21 | 11.06 | 17.04 | 0.0137 | NA | NA | 17.4 | 102 |
20 (M, 5y) | 2008 | 110 728 | 28 | AA | 2 | 17 [2] | 28[35] | 30 | 7 | 7 | 35.60 | 4.67 | 0.0542 | 10 | 27 | NA | NA |
Mean | |||||||||||||||||
Age (3.3y) | Ā | 100 418b | 26.86 | Ā | 1.14 | 22.43 | 27.6 | 30.14 | 11 | 10.5 | 33.95 | 8.14 | 0.023 | 10.98 | 29.64 | 17.4 | 102 |