Table 2 Clinical and laboratory findings of confirmed dengue patients estratified by age-group
Features | < 15 years N = 42 (%) | ≥ 15 years N = 410 (%) | P a |
|---|---|---|---|
Signs and symptoms reported or observed during recruitment | |||
Age, years - median (min-max) | 10.1 (0–14) | 38.4 (15–83) | – |
Female sex | 25 (59.5) | 210 (51.2) | 0.305 |
Days of illness - median (min-max) | 4 (2–8) | 5 (1–13) | 0.535g |
Headache | 36 (85.7) | 335 (81.7) | 0.519 |
Prostration | 41 (97.6) | 373 (91.0) | 0.139 |
Rash | 29 (69.0) | 269 (65.6) | 0.654 |
Vomit | 23 (54.8) | 175 (42.7) | 0.133 |
Signs and symptoms reported or observed during the course of the disease | |||
Spontaneous bleeding | 20 (47.6) | 109 (26.6) | 0.004 |
Gastrointestinal bleeding | 3 (7.1) | 22 (5.4) | 0.631 |
Neurological alterations | 1 (2.4) | 24 (5.9) | 0.346 |
Breathing difficulties | 0 | 51 (12.4) | 0.015 |
Icterus | 1 (2.4) | 17 (4.1) | 0.576 |
Intense abdominal pain | 12 (28.6) | 66 (16.1) | 0.042 |
Hepatomegaly | 3 (11.1) | 24 (5.9) | 0.737 |
Effusions and Ascites | 4 (9.5) | 8 (2.0) | 0.004 |
Main laboratory results during the course of the disease | |||
Hemoconcentrationb | 12 (29.3) | 77 (19.6) | 0.146 |
Leukopenia (< 4000 cel/ml)c | 20 (50.0) | 230 (58.4) | 0.223 |
Thrombocytopenia (< 100.000 cel/ml)d | 9 (22.0) | 123 (31.1) | 0.307 |
AST (> 1000)e | 0 | 0 | – |
ALT (> 1000)f | 0 | 0 | – |
Clinical classification | |||
Dengue Fever | 12 (28.6) | 176 (42.9) | 0.075 |
Dengue with Warning Signs | 27 (64.3) | 211 (51.5) | 0.103 |
Severe Dengue | 3 (7.1) | 23 (5.6) | 0.307 |
Antibody response patternh | |||
Primary | 13 (39.4) | 67 (22.7) | 0.034 |
Secondary | 20 (60.6) | 228 (77.3) | 0.034 |