Table 4 Multinomial analysis of the association between antibody response pattern, serotype and severity of dengue disease as outcome
Parameters | Dengue Fever | Dengue with Warning Signs | Severe Dengue | ||||
|---|---|---|---|---|---|---|---|
N = 188 (%) | N = 238 (%) | OR (95% CI) | P-value | N = 26 (%) | OR (95% CI) | P-value | |
Gender | |||||||
Female | 78 (41.5) | 143 (60.1) | 2.12 (1.44–3.13) | 0.000 | 14 (53.8) | 1.64 (0.72–3.75) | 0.236 |
Age group (years) | |||||||
< 15 | 12 (6.4) | 27 (11.3) | Reference | – | 3 (11.5) | Reference | – |
≥ 15 | 176 (93.6) | 211 (88.7) | 0.53 (0.26–1.08) | 0.082 | 23 (88.5) | 0.52 (0.14–1.99) | 0.342 |
Comorbidity | 46 (24.5) | 60 (25.2) | 1.04 (0.67–1.62) | 0.860 | 9 (34.6) | 1.63 (0.68–3.92) | 0.271 |
Antibody response patterna | |||||||
Primary | 53 (28.2) | 62 (26.1) | Reference | – | 3 (11.5) | Reference | – |
Secondary | 121 (64.4) | 146 (61.3) | 1.03 (0.66–1.60) | 0.890 | 18 (69.2) | 2.63 (0.74–9.30) | 0.134 |
Serotypeb | |||||||
DENV-1 | 35 (19.7) | 47 (19.7) | Reference | – | 9 (34.6) | NA | – |
DENV-4 | 63 (35.4) | 72 (30.3) | 0.85 (0.49–1.48) | 0.568 | 0 | NA | – |