Study site | River Basin, Senegal |
---|---|
Included | 81 children (7–12 years of age) with high susceptibility of being infected |
Prevalence before PZQ | 89% (72 children) based on individual UCAA10 diagnosis |
 | 100% (81 children) based on individual UCAA250 diagnosis |
CAA level 1 | 519Â pg/ml |
Prevalence after PZQ | 43.2% (35 children) based on individual UCAA10 diagnosis |
 | 86.4% (65 children) based on individual UCAA250 diagnosis |
CAA level 1 | 33Â pg/ml |
POOLING | Pooling of samples collected after PZQ treatment |
Pool composition | Nine pools, each comprising an equal volume of 9 children –‘9 sample pool’ |
One pool comprising an equal volume of all 81 samples – ‘81 sample pool’ | |
Applied test | Pools were analysed with the UCAA250 format |
CAA level 9-sample pool 1 | 47, 84, 29, 57, 60, 36, 22, 40, 33 pg/ml – average of nine ‘9 sample pools’ 45 pg/ml |
CAA level 81-sample pool 1 | 40Â pg/ml |