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Table 1 Demographics and clinical characteristics of HIV-infected patients with PTB

From: Risk factors affecting the mortality of HIV-infected patients with pulmonary tuberculosis in the cART era: a retrospective cohort study in China

 

Overall

N = 359

Survivals

N = 280

Deaths

N = 53

P value

Age, Years, median (IQR)

39 (31,52)

39 (29,48)

49 (35,63)

< 0.001

Male gender N (%)

325 (90.53%)

254 (90.71%)

48 (90.57%)

1.000

On cART N (%)

98 (27.30%)

83 (29.64%)

8 (15.09%)

0.029

Diagnostic delaya N (%)

153 (42.60%)

106 (37.86%)

36 (67.92%)

< 0.001

Extrapulmonary Involvement

49 (13.65%)

35 (12.50%)

12 (22.64%)

0.052

Clinical symptoms

 Fever (> 39 °C) N (%)

263 (73.26%)

207 (73.93%)

32 (60.38%)

0.044

 Cough N (%)

181 (50.42%)

144 (51.43%)

28 (52.83%)

0.851

 Expectoration N (%)

82 (22.84%)

61 (21.79%)

17 (32.08%)

0.105

 Anorexia N (%)

81 (22.56%)

60 (21.45%)

13 (24.53%)

0.617

 Dyspnea N (%)

69 (19.22%)

49 (17.50%)

16 (30.19%)

0.033

Complications

 Bacterial pneumonia N (%)

32 (8.91%)

18 (6.43%)

14 (26.42%)

< 0.001

 HBV/HCV co-infection N (%)

25 (6.96%)

19 (6.79%)

6 (11.32%)

0.387

 Syphilis N (%)

33 (9.19%)

30 (10.71%)

1 (1.89%)

0.077

 Diabetes N (%)

14 (3.90%)

11 (3.93%)

2 (3.77%)

1.000

 Hypertension N (%)

12 (3.345%)

9 (3.21%)

2 (3.77%)

1.000

Laboratory examination

 Sputum smear positive N (%)

156 (43.45%)

126 (45.00%)

21 (39.62%)

0.470

 Sputum culture positive N (%)

180 (50.14%)

141 (50.36%)

23 (43.40%)

0.353

 T-spot. TB test positive N (%)

227 (63.23%)

181 (64.64%)

30 (56.60%)

0.265

 HIV RNA lg copies/ml median (IQR)

5.17 (3.91,5.66)

5.14 (3.83,5.65)

5.32 (4.61,5.79)

0.354

 CD4+ T cell/mm3 median (IQR)

51 (23 116)

55 (27 122)

24.5 (10,86)

0.001

Manifestation of lung CT scan

 Extensive pulmonary lesionb N (%)

218 (60.72%)

160 (57.14%)

41 (77.36%)

0.006

 Pulmonary cavity N (%)

36 (10.03%)

25 (8.93%)

9 (16.98%)

0.076

 Pulmonary atelectasis N (%)

31 (8.64%)

20 (7.14%)

9 (16.98%)

0.039

  1. aDiagnostic delay was defined as the pulmonary TB was diagnosed in more than four weeks after the onset of symptoms
  2. bExtensive pulmonary lesion was defined as TB lesions involved more than 3 pulmonary lobes by chest CT scan