Infectious Diseases of Poverty

Table 1 E. granulosus worm burdens at day 45 post-infection in Beagles vaccinated with rEgM9/ Quil A adjuvant

From: Dog vaccination with EgM proteins against Echinococcus granulosus

Group (protein)	Dog No.	Number of worms
		Total	≤3 seg	%	≥4 seg	%	Gravid Seg	%
GST controls	71 122	17 154	8025	46.8	7445	43.4	1684	9.8
	71 123	43 725	16 425	37.6	17 833	40.8	9467	21.7
	71 124	14 543	4908	33.7	7452	51.2	2183	15.0
	71 125	34 779	14 792	42.5	15 162	43.6	4825	13.9
	71 126	18 909	9233	48.8	8267	43.7	1409	7.5
	71 127	32 606	16 333	50.1	8867	27.2	7406	22.7
	71 129	19 204	6358	33.1	9912	51.6	2934	15.3
	Average	25 846	10 868	42.0	10 705	41.4	4273	16.5
	SD	11 111	4878	–	4120	–	3114	–
	Median	19 204	9233	48.1	8867	46.2	2934	15.3
	IQR	(17 154, 34 779)	(6358, 16 333)	–	(7452, 15 162)	–	(1684,7406)	–
EgM9	71 112	21 008	20 496	97.6	512	2.4	0	0.0
	71 113	9229	8475	91.8	754	8.2	0	0.0
	71 114	9340	4588	49.1	4752	50.9	0	0.0
	71 115	12 824	12 342	96.2	482	3.8	0	0.0
	71 116	1558	1558	100.0	0	0.0	0	0.0
	71 117	28 801	19 651	68.2	8783	30.5	367	1.3
	71 128	30 746	26 083	84.8	4167	13.6	496	1.6
	Average	16 215	13 313	82.1	2779	17.1	123	0.8
	SD	10 916	9069	–	3269	–	214	–
	Median	12 824	12 342	96.2	754	5.9	0	0
	IQR	(9229, 28 801)	(4588, 20 496)	–	(482, 4752)	–	(0, 367)	–
	Redu %^a	33.2	–	–	–	–	100	–
	P value^b	0.128	0.655	–	0.004	–	0.001	–

^aCompared to those in the GST group. Redu, reduction = (worm burden median in GST-worm burden median in the experiment group)/worm burden median in GST group × 100%. ^bThe Mann-Whitney U test was used to compare the worm burden median. P value less than 0.05 means that reduction is significant between GST and experimental groups using median analysis. The meaning of ^{a, b}is the same in the following tables

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ISSN: 2049-9957

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