Variable | Total No. | No. with PRRD2 ≥ 10 000 | OR (95% CI) | P value | aOR (95% CI) | P value |
---|---|---|---|---|---|---|
Gender | ||||||
 Female | 424 | 202 | 1 |  |  |  |
 Male | 495 | 240 | 1.0 (0.8–1.3) | 0.85 | – | – |
Age (month) | ||||||
  ≤ 30 | 284 | 121 | 1 |  | 1 |  |
  > 30 | 629 | 320 | 1.4 (1.1–1.9) | 0.02 | 1.4 (1.0–1.9) | 0.03 |
Duration of illness (days) | ||||||
  ≤ 2 | 269 | 163 | 1 |  |  |  |
  > 2 | 334 | 194 | 1.3 (0.8–2.0) | 0.59 | – | – |
Haematocrit at presentation (%) | ||||||
  < 31 | 465 | 201 | 1 |  | 1 |  |
  ≥ 31 | 434 | 236 | 1.6 (1.2–2.0) | 0.001 | 1.5 (1.1–1.9) | 0.01 |
Haematocrit on day 1 (%) | ||||||
  < 30 | 407 | 123 | 1 |  |  |  |
  ≥ 30 | 483 | 226 | 0.8 (0.6–1.0) | 0.11 | – | – |
History of fever before treatment | ||||||
 Absent | 170 | 75 | 1 |  |  |  |
 Present | 749 | 367 | 1.2 (0.9–1.7) | 0.29 | – | – |
Temperature at presentation (°C) | ||||||
  ≤ 37.4 | 349 | 125 | 1 |  | 1 |  |
  > 37.4 | 570 | 317 | 2.2 (1.7–3.0) | < 0.0001 | 2.0 (1.5–2.7) | < 0.0001 |
Fever on day 1* | ||||||
 Absent | 797 | 394 | 1 |  |  |  |
 Present | 103 | 47 | 0.9 (0.6–1.3) | 0.53 | – | – |
Enrolment Parasitaemia | ||||||
  ≤ 105 | 823 | 380 | 1 |  | 1 |  |
  > 105 | 96 | 62 | 2.1 (1.4–3.3) | < 0.0001 | 1.9 (1.2–3) | 0.01 |
PRRD1 | ||||||
  ≤ 103 | 501 | 205 | 1 |  | 1 |  |
  > 103 | 418 | 237 | 1.9 (1.5–2.5) | < 0.0001 | 2.1 (1.6–2.7) | < 0.0001 |
Gametocytaemia | ||||||
 Present | 48 | 10 | 1 |  | 1 |  |
 Absent | 871 | 432 | 3.7 (1.8–7.6) | < 0.0001 | 2.4 (1.1–5.0) | 0.02 |
Drug treatment | ||||||
 AL | 303 | 141 | 1 |  |  |  |
 AA | 295 | 144 | 1.1 (0.8–1.5) | 0.64 | – | – |
 DHP | 321 | 157 | 1.1 (0.8–1.5) | 0.61 | – | – |