Control programs for strongyloidiasis in areas of high endemicity: an economic analysis of different approaches

Table 1 Data input of the mathematical model for the case base scenario

Population data	%	Number	Refs
Total population		1 000 000
School age population (6–14 years)	0.25	250 000	[13]
Adult population (≥ 15 year)	0.50	500 000	[13]
School age (6–14 years) participating to the survey	0.001	1000	*
Adults (≥ 15 year) participating to the survey	0.000		*

Strongyloides stercoralis infection and treatment data	Case base scenario (%)	Min.	Max.	Refs
Strongyloidiasis prevalence in school age population (6–14 years)	0.150	0.10	0.20	[2]
Strongyloidiasis prevalence in adults (≥ 15 year) estimated with the survey	0.270	0.18	0.36	[2]
Compliance to ivermectin treatment in school age group (6–14 years)	0.80	0.75	0.85	[14]
Compliance to ivermectin treatment in adults (≥ 15 year)	0.60	0.55	0.65	[14]
Treatment cure rate (is the same in all age groups)	0.86	0.79	0.91	[15]
Re-infection or new infection rate in school age group (6–14 years)	0.50	0.45	0.55	[16]
Re-infection or new infection rate in adults (≥ 15 year)	0.50	0.45	0.55	[16]

Costs in dollars	Case base scenario	Min.	Max.	Refs
Cost of survey per person (Baerman / ELISA + additional costs such as logistics etc.…)	27.00			§
Cost of ivermectin for 1 school age child	0.10	0.05	0.20	[21]
Cost of ivermectin for 1 adult	0.30	0.20	0.40	[21]
Cost of ivermectin administration at school	0.015	0.01	0.02	[20]
Cost of ivermectin administration to adults	0.50	0.25	0.75	[19]

*Based on expert’s opinion. § Buonfrate D. personal communication from a pilot project in Ethiopia

ISSN: 2049-9957