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Table 2 Characteristics of the studies included to assess the demographic characteristics, co-morbidities and clinical warning signs of severe dengue

From: Clinical predictors of severe dengue: a systematic review and meta-analysis

Parameters

Frequency (n)

Percentage (%)

WHO Classification type

 1997

58

40.6

 2009

85

59.4

WHO region

 South-East Asia

74

51.8

 Western Pacific

33

23.1

 American

26

18.2

 Eastern Mediterranean

7

4.9

 European

2

1.4

 Africa

1

0.7

Study design

 Case control

26

18.2

 Cohort

36

25.2

 Cross-sectional

81

56.6

Study population

 Children

59

41.3

 Adults

36

25.2

 Mixed

47

32.9

 No information

1

0.7

Recruitment year

 1990–2010

78

54.6

 2011–2019

64

44.8

 No information

1

0.7

Laboratory diagnosis

 ELISA

96

67.1

 PCR

49

34.3

 RDT

27

18.9

 HI

10

7.0

 Viral culture

4

2.8

 Immunohistochemistry

2

1.4

 Immunofluorescence assay

1

0.7

 Neutralization test

1

0.7

 Dotblot immuno assay

1

0.7

 No information

13

9.1

  1. ELISA enzyme linked immunosorbent assay, PCR polymerase chain reaction, RDT rapid diagnostic test, HI haemagglutination inhibition