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Table 3 Comparison of neurocognitive and behavioral outcomes among uninfected, mild tungiasis, and severe tungiasis groups—adjusted means and group differences corrected for effects of covariates

From: Neurocognitive and mental health outcomes in children with tungiasis: a cross-sectional study in rural Kenya and Uganda

Outcomes

Uninfected

Mild tungiasis

Severe tungiasis

Overall group differences

Uninfected vs mild disease

P-value*

Uninfected vs severe disease

P-value*

Main domain

Sub-domain

Adjusted mean (SE)

Adjusted mean (SE)

Adjusted mean (SE)

F

df

P-value

Partial eta squared

  

Language

Literacy ability

99.0 (2.61)

86.1 (3.78)

93.8 (3.75)

3.73

2,434

0.024

0.016

 < 0.001

0.014

Language

24.4 (0.44)

22.1 (0.63)

24.2 (0.63)

4.53

2,434

0.011

0.02

 < 0.001

0.169

Attention

Cognitive flexibility

41.3 (1.35)

35.2 (1.96)

43.8 (1.95)

5.35

2,434

< 0.001

0.024

0.008

0.873

Response inhibition

37.7 (0.59)

36.6 (0.86)

36.4 (0.85)

1.03

2,434

0.356

0.004

  

Memory

Working memory

2.9 (0.09)

2.5 (0.12)

2.7 (0.12)

3.61

2,434

0.027

0.016

0.001

0.097

Perceptual-motor

Fine motor ability

10.1 (0.11)

9.8 (0.16)

9.5 (0.16)

4.37

2,434

0.013

0.02

0.002

 < 0.001

Executive functioning

Nonverbal intelligence

13.2 (0.37)

13.3 (0.54)

13.8 (0.53)

0.34

2,434

0.710

0.001

  

Numeracy ability

40.4 (0.77)

39.1 (1.12)

38.5 (1.11)

1.07

2,434

0.342

0.004

  

Behavioral outcomes

  

 Total behavioral problems

30.0 (1.49)

31.8 (2.16)

37.1 (2.14)

3.51

2,434

0.03

0.016

0.858

0.023

  1. All P-values are from Analysis of Covariance. Covariates adjusted for included age, sex, grade, nutritional status, care giver education, disability, school absenteeism and socioeconomic status
  2. SE standard error
  3. *Scheffe Test for pairwise comparison of means