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Fig. 6 | Infectious Diseases of Poverty

Fig. 6

From: A potential transition from a concentrated to a generalized HIV epidemic: the case of Madagascar

Fig. 6

Conceptual model of HIV progression from concentrated epidemic to generalized and self-maintained epidemic in countries with the socio-behavioural characteristics of Madagascar. The start up of the epidemic is characterized by a long-lasting and steady increase of HIV prevalence among SWs. HIV infection spills over to GP (adult females, AGYW and indirectly other GP males) through bridge population (SW clients, see red arrows). The intensity of this initial spillover is enhanced as prevalence among SW increases in a positive feedback manner. Once a certain threshold in GP has been reached, prevalence/incidence in GP may be self-sustained and tend to increase through high risk intercourse between AGYW and older adults. This threshold may be reached sooner depending on the prevalence of age disparate relationships, concurrency and inconsistent use of condoms. Transactional sex may be the main mediator of such risk factors. SW  sex workers, GP  general population, AGYW  adolescent girls and young women

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