Effectiveness of ivermectin mass drug administration in the control of soil-transmitted helminth infections in endemic populations: a systematic review and meta-analysis

Table 3 Odds of prevalence reduction, stratified by STH

	Odds ratio (95% CI)	P	R²
S. stercoralis (N = 8)
Baseline prevalence (%)	0.99 (0.80–1.23)	0.922	0.218
Number of chemotherapy rounds	1.16 (0.95–1.43)	0.119
Follow-up time after last round (months)	1.06 (0.84–1.34)	0.571
T. trichiura (N = 9)
Baseline prevalence (%)	0.95 (0.90–0.99)	0.041	0.303
Number of chemotherapy rounds	1.35 (0.85–2.14)	0.109
Follow-up time after last round (months)	0.94 (0.83–1.07)	0.171
Hookworm (N = 30)
Baseline prevalence (%)	1.01 (0.93–1.10)	0.759	0.257
Number of chemotherapy rounds	1.82 (1.21–2.73)	0.008
Follow-up time after last round (months)	0.90 (0.70–1.18)	0.444
A. lumbricoides (N = 11)
Baseline prevalence (%)	0.82 (0.70–0.96)	0.027	0.748
Number of chemotherapy rounds	0.93 (0.36–2.40)	0.849
Follow-up time after last round (months)	1.07 (0.68–1.66)	0.708

Random effects weighted meta-regression with robust clustered standard errors
Embolden values indicate statistically significant results at the P < 0.05 level
S. stercoralis analysis included studies using ivermectin, with or without albendazole
T. trichiura, hookworm, and A. lumbricoides analyses included studies using ivermectin and albendazole

ISSN: 2049-9957