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Table 2 Demographic and epidemiological characteristics of 880 brucellosis cases at the time of enrollment

From: Incidence and warning signs for complications of human brucellosis: a multi-center observational study from China

Variables

Subgroups

Total

N = 880

n (%)

Complicated

N = 482

n (%)

Uncomplicated

N = 398

n (%)

P value

Gender

Male

642 (73.0)

354 (73.4)

288 (72.4)

0.719

Female

238 (27.0)

128 (26.6)

110 (27.6)

 

Age group

< 60 years

702 (79.8)

369 (76.6)

333 (83.7)

0.009

≥ 60 years

178 (20.2)

113 (23.4)

65 (16.3)

 

Nationality

Han nationality

614 (69.8)

353 (73.3)

261 (65.6)

0.014

Minority nationality

266 (30.2)

129 (26.7)

137 (34.4)

 

Occupation

Farmer& Herdman

754 (85.7)

418 (86.7)

336 (84.4)

0.234

Animal and animal products processing management

49 (5.6)

21 (4.4)

28 (7.0)

 

Other occupationsa

77 (8.8)

43 (8.9)

34 (8.5)

 

Region

Xinjiang

385 (43.8)

206 (42.7)

179 (45.0)

0.426

Shandong

289 (32.8)

155 (32.2)

134 (33.7)

 

Inner Mongolia

206 (23.4)

121 (25.0)

85 (21.4)

 

Education

Primary or below

364 (41.4)

216 (44.8)

148 (37.2)

0.051

Junior high school

394 (44.8)

199 (41.3)

195 (49.0)

 

High school or above

122 (13.9)

67 (13.9)

55 (13.8)

 

Exposure historyd

Exposure to animals

830 (94.3)

442 (91.7)

388 (97.5)

< 0.001

Sheep & goats

774 (88.0)

417 (86.5)

357 (89.7)

0.149

Cattle

328 (37.3)

170 (35.3)

158 (39.7)

0.176

Other animalsb

22 5 (27.1)

145 (32.8)

80 (20.6)

< 0.001

Method of exposures to animalsd

Raising

691 (78.5)

387 (80.3)

304 (76.4)

0.160

Grazing

356 (40.5)

176 (36.5)

180 (45.2)

0.009

Slaughter

222 (25.2)

132 (27.4)

90 (22.6)

0.105

Delivering lambs

414 (47.1)

239 (49.6)

175 (44.0)

0.097

Other routesc

369 (41.9)

195 (40.5)

174 (43.7)

0.329

Ingestion of unpasteurized food

Yes

130 (14.8)

97 (20.2)

33 (8.3)

< 0.001

No

748 (85.2)

383 (79.8)

365 (91.7)

 

Family history of brucellosis

Yes

183 (21.1)

96 (20.2)

87 (22.1)

0.489

No

685 (78.9)

379 (79.8)

306 (77.9)

 

Previous history of brucellosis

Yes

77 (8.8)

42 (8.7)

35 (8.8)

0.967

No

803 (91.2)

440 (91.3)

363 (91.2)

 

Days from onset to diagnosis

0–7

166 (18.9)

72 (14.9)

94 (23.8)

< 0.001

8–30

425 (48.5)

219 (45.4)

206 (52.2)

 

31–90

207 (23.6)

132 (27.4)

75 (19.0)

 

 > 90

79 (9.0)

59 (12.2)

20 (5.1)

 

Clinical stagee

Acute

793 (90.1)

419 (86.9)

374 (94.0)

0.002

Subacute

50 (5.7)

38 (7.9)

12 (3.0)

 

Chronic

37 (4.2)

25 (5.2)

12 (3.0)

 

Underlying disease

Yes

311 (35.3)

198 (41.1)

113 (28.4)

< 0.001

No

569 (64.7)

284 (58.9)

285 (71.6)

 

Hospitalized

Yes

614 (71.8)

395 (84.6)

219 (56.4)

< 0.001

No

241 (28.2)

72 (15.4)

169 (43.6)

 
  1. Those with missing values were excluded from analysis. Percentages may not sum to 100 due to rounding
  2. aOther occupations include staff, student, teacher, and other non-occupational population with brucellosis
  3. bOther animals include pigs, dogs, horses, deer, and camels
  4. cOther routes include veterinarian, animal trade, animal product processing and sheep clipping
  5. dPatients may have a history of multiple animal contacts or exposure modes. Therefore, the cumulative total may exceed 100%
  6. eInter-group comparison with the method of Bonferroni found that the proportion of complications among the three groups was different